Pin point help

[Project wizard] - [select source file] - [Content of video]

At [Content of video], specifies information of source video
By inputting appropreate value, TMPGEnc encodes in most optimized method.

Video movie | The source consists only from video movie(29.97fps progressive/interlaced) Select this option if you are trying to encode movies captured from digital camera.
Film movie | The source consists only from film movie(substantially 24fps). This mode can be used for 29.97fps interlaced file movie. Select this option if you are trying to encode film / anime movies.
Video/Film mixed | Select this option if you have mixed source.

If your source is none of the above, select "Video movie".